Friday, February 28, 2020

Strategic management Essay Example | Topics and Well Written Essays - 2000 words - 2

Strategic management - Essay Example They are accountable for the success of the organization. For instance, managers offer objectives and vision of the managerial goal, and plan to execute the goals. Strategic managers are also in charge of plans and policies of an organization (Expansion Management, 2009). Any organization should have the strategic management branch, which sets up mission for the company. Managerial activity encompasses information about the organization and functioning. Strategic management is a particularly crucial responsibility accomplished mostly by a single individual, and in most cases, the future success of an organization depends on the strategic management. The strategic management process is based on the transformation of working process of where the organization is at presently, and where it wants to be after some time. Transformation process is based on the people within the business, and should be by two way process where every person in the business is involved in executing the set goal s and objectives (Samsung, 2009). Samsung Electronics is a multinational electronics company in South Korea with its headquarters at Suwon. The company is a flagship subsidiary of the Samsung group, which forms the largest information technology company in the world with the highest revenue. The company was established in 1969 for manufacturing of black and white television sets, 5-business decisions, and Dynamic Random Access Memory (DRAM). Samsung electronics has sales network and assembly plants in 61 countries worldwide with 221,000 employees. The company forms the largest mobile phone company in the world by unit sales in 2011. The company has the highest world market share in memory chip and has an established position in the tablet market (Samsung, 2009). Strategic management in Samsung Electronics The past few years in Samsung Electronics have been an immense advancement with different technologies taking the limelight like the liquid crystal display over cathode ray tube (C hiu et al. 2006, p. 143-165). In this paper, the strategies employed the liquid crystal display (LCD) and the dynamic random access memory (DRAM) are analyzed (Samsung, 2009). Samsung Electronics in LCD market Lee Kun-hee changed the strategy in Samsung group in 1993 from the imitating cost-leader to differentiator role through concentrating and downsizing the engineering, electronics and chemical industries. In 1995, the company had already developed the LCD technology and achieved considerable market. Since then, the company has achieved a flagship with the revenues increasing consistently over the years. The company has the highest global share in LCD (Moon, 2009). The strategic management in LCD is applicable to both internal and external environments, which are further subdivided into sections. External Environment in Samsung Electronics Company (LCD) External environment encompasses both the industry and the environments that are used in assessing the strategic position of the Samsung Electronics Company. The macro environment entails all the external factors that affect planning and performance in the company. These include the social factors, technological factors, political factors, economic factors, environmental factors and legal

Tuesday, February 11, 2020

Morpholins anti-cancer drugs Dissertation Example | Topics and Well Written Essays - 3250 words

Morpholins anti-cancer drugs - Dissertation Example They produced morpoline derivatives which included both esters and N-alkyl derivatives. The target compounds were characterised using H1, C13NMR, IR and were studied as inhibitors of ÃŽ ²-D-galactosidase extracted from Bovine kidney. The activity of this enzyme is associated with a variety of diseases therefore the produced morpholine derivatives have potential medical applications. p-nitrophenyl-ÃŽ ²Ã¢â‚¬â€œD-galactopyranoside was chosen as a substrate for the enzymatic cleavage of the carbon-oxygen bond which is catalysed by ÃŽ ²-D-galactosidase. During the process p-nitrophenol was released in the environment, the compound had the ability to absorb light in the visible region of the electromagnetic spectrum, therefore, it was possible to estimate its quantity using the Beer–Lambert–Bouguer law. By measuring the quantity of the produced p-nitrophenol at set time intervals conclusions were drawn regarding the reaction speed and, consequently, about inhibition propertie s of the studied morpoline derivative. The reaction was followed by Michaelis-Menten kinetics, therefore reaction speed was calculated using the most linear fragment in the dependence between absorption and time. Because the enzyme was denatured, its inhibitory properties were not tested and are a subject for future work. Cell’s surface is composed of lipids, carbohydrates and proteins. Compared to other surface molecules glycolipids and glycoproteins are the longest. For this reason they are often take part in interactions with substrates or other cells, consequently carbohydrates are of paramount importance in cellular interactions and disease processes such as cancer, infections or inflammations. ... The compound can covalently attach to serine or threonine. The process leads to formation of clusters in which one monosaccharide is linked to one amino acid. The produced clusters are often the ideal targets for antitumor antibodies. Such antibodies can be generated by glycopeptides linked to clustered sialyted epitopes. The effectiveness of which is usually higher then single sialyted epitopes (Butters, et al., 2003). Glycosidases classification is based on the similarities in the sequence of their amino acids (Table 1) (Henrissat and Bairoch, 1993; Henrissat, 1991). Enzymes within the same group share the same structural features and perform their functions using the same mechanism (Rye and Withers, 2000) Usually, there are two mechanisms employed by enzymes to cleave glycosidic bonds. As a result, a free hydroxyl group is formed with retention or inversion of configuration (Scheme 1)(Sinnott, 1990; Zechel and Withers, 2000; Vasella, et al., 2002). In the mechanism (a) glycosidase s cleave the required bonds using asparagine and glutamine 6A apart from each other. One carboxylic group is deprotonated an acts as a base by abstracting a proton from water during the formation of the intermediate (Withers and Umezawa, 2001; Davies, et al., 2005; Hoj, et al., 1992). Table 1. Type of carbohydrate-active enzyme and its function Carbohydrate-active enzyme Abbreviation Function Carbohydrate Esterases CE Carbohydrate esters hydrolysis Polysaccharide Lyases PL Non-hydrolytic cleavage of glycoside bonds GlycosylTransferases GT Glycosidic bonds formation Glycoside Hydrolases GH Glycosidic bonds rearrangement or hydrolysis The remaining carboxylic group protonates the oxygen atom from the anomeric centre and assists in its removal. Both bond formation and